Cardarine (GW-501516) is a PPARδ agonist and NOT a SARM, but does work in very similar ways. GW-501516 targets the androgen receptors that stimulate glucose uptake and skeletal muscle tissue. Because of this it is being suggested as a potential future treatment for obesity due to its ability to quickly cause fatty acid oxidation. Cardarine is also suggested to increased HDL levels (good cholesterol) by 79% and decreased LDL (bad cholesterol).
It has become a legend in the world of sports and athleticism due to its ability to burn off excess fatty tissue, enhance recovery, and dramatically increase endurance. GW-501516 generates proinflammatory markers in adipose tissue and decreasing the activity of genes involved in lipogenesis. This means that the body is able to block fatty acid chains from forming and being stored as fat. It is literally the best it gets when it comes to endurance, energy, stamina, and performance enhancement of any kind.
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GW 501516 (or Cardarine), is a research chemical developed in the 1990s to prevent and cure tumor formation in the colon, prostate, and breasts. Studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to stop metabolic disorders such as obesity and diabetes through specific gene expressions.
As research continued to grow, bodybuilders quickly caught on to GW 501516, calling it “the ultimate endurance enhancing supplement.”
Plus, Cardarine’s ability to burn off excess fatty tissue, enhance recovery, and dramatically increase endurance has made this product a staple in every athlete’s cycle and PCT. With no harmful side effects found in the past 20 years, no wonder why GW 501516 has become a legend in the world of sports and athleticism.
How It Works
GW501516 is is a PPARδ agonist and NOT a SARM, but does work in very similar ways. In this case, GW 501516 targets the androgen receptors that stimulate glucose uptake and skeletal muscle tissue. Currently, it is being suggested as a potential treatment for obesity by rapidly melting through what’s called “fatty acid oxidation“.
Also, Cardarine is said to increase HDL by an average of 79% (good cholesterol) and decrease LDL (bad cholesterol) in current Phase II trials.
These help increase your HDL levels from an enhanced expression of the cholesterol transporter ABCA1.
The Benefits of GW 501516
The benefits of Cardarine seem to be endless, both in medical science and in the gym. Many studies have been done on GW 501516 showing numerous positive effects during the trial, despite minimum side effects.
That is part of the reason why Cardarine has recently become so popular.
Below is a list of the most powerful benefits that you could experience while taking a cycle of GW 501516 (compiled from much research and study)
The Ultimate Endurance Supplement
GW 501516 is literally the best it gets when it comes to endurance, energy, stamina, and performance enhancement of any kind.
It is used by elite athletes for a reason, from cyclists to elite bodybuilders. In fact, WADA has even added GW 501516 to their list of banned substances because of its competitive advantage.
You can expect insane levels of intensity in the gym, shorter recovery times, and be able to bust through plateaus like never before.
Also, the energy you get from Cardarine is not experienced as jittery or anxious. It’s not a stimulant, and you won’t crash hours later.
In fact, many users even report feeling an overall sense of well being and calmness.
Some of the other benefits include:
• Rapidly melts fat and NON-catabolic;
• Provides noticeable results on the first dose;
• The ability to run for as long as 8-12+ weeks;
• Is versatile and can be stacked with anything;
• Can be used while cutting OR bulking;
• No side effects, liver toxicity, or suppression have been reported;
• No need for a PCT.
Cardarine: The Cure for Obesity?
The primary role of GW’s ability to rid the body of unwanted fatty tissue is almost LEGENDARY. The chemical compounds in this particular PPAR agonist functions in the differentiation of adipocytes.
Much like growth hormone, GW501516 generates proinflammatory markers in adipose tissue and decreasing the activity of genes involved in lipogenesis. This means that the body is able to block fatty acid chains from forming and being stored as fat.
A study from Scientific Reports published in 2015 stated:
“GW501516 acts on PPAR beta cells that exclusively use body fat as energy in the same way the body would when going through “starvation mode”.
The study is quoted stating: “physiological and pathophysiological functions of PPAR and generated novel strategies to treat metabolic diseases”.
The activation of these particular genes in the body has been seen to burn body fat at such an alarming rate that it is being coined “the cure to obesity”.
There were absolutely no adverse side effects detected in the last 20 years of study and it was extremely rare to see muscle wasting at any point during the research.
Cardarine’s Effects on Muscle Fibers
The 2015 study by Wei Chen, Ph.D. and his colleges has also found that dramatic increases in the PPAR gene in slow twitch muscle fibers increases oxygen usage and greatly increases endurance. The enhanced endurance was seen in lab mice with a normal oxygen supply and those with oxygen restrictions which provided significant evidence that GW501516 targets and enhances skeletal muscle endurance and recovery time to a supraphysiological level.
A study titled “A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice” stated that BCAA were spared during trials of intense exercise which allowed the mice to have a greater rate of recovery in muscle tissue and neurotransmitters.
These rats had even lost weight while maintaining a high-fat diet, suggesting it could potentially prevent obesity and help manage weight regardless of diet or lifestyle.
This compound has a long range of proven benefits. The results you can expect while cycling with Cardarine include:
• Boost in energy levels: This compound helps you boost your energy levels when you are on a cutting diet. It helps you train longer and harder. You will feel the difference considerably when you are lifting as it improves your strength levels.
• Fat loss: Cardarine increases the rate at which stored fat is converted into energy by our body. In this way, you lose fat quickly and look leaner.
• Improved recovery: This compound leads to increased oxygen use by increasing the PPAR gene expression located in slow twitch muscle fibres. In this way, it improves your recovery rate and enables you to recover faster and workout more frequently.
• Muscle Building: This anabolic compound helps you gain considerable muscle mass. It is a must-have compound if you want to put on some good muscles. It helps in muscle growth by developing existing cells and forming new cells. You should definitely add this to your bodybuilding diet for quick results.
Take 1 (one) to 2 (two) capsules daily. One preferably in the morning and another in the afternoon or 30/45 minutes before workout.
For maximum results continue cycle for 8 weeks with 30 day break.
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